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Alpha Preclinical
About CRO
Alpha Preclinical is a discovery-focused Contract Research Organization (CRO) dedicated to accelerating preclinical research through tailored in vivo and in vitro services. Founded by Barak Yahalom, D.V.M, Joan, F, Flanagan PhD, and Mr. Shay Gonen. Alpha Preclinical bridges the gap between innovative research and clinical translation. Based in Worcester, MA, we partner with biotech and pharmaceutical organizations to deliver high-quality, cost-effective studies with a focus on operational efficiency, transparency, and scientific excellence.
Why Choose Alpha Preclinical?
● Scientific Expertise: Decades of experience in in-vivo and in-vitro research, led by founding scientists with deep knowledge of translational medicine.
● Tailored Solutions: Customized study designs to meet specific research objectives, ensuring flexibility and precision.
● Operational Efficiency: Rapid study initiation (within ~3 weeks) and seamless execution to accelerate timelines.
● Transparency: Clear communication of study details and progress, fostering trust and long-term partnerships.
● Customer-Centric Approach: A collaborative interface that prioritizes client needs and delivers actionable, high-quality data.
Contact Us
Empower your preclinical research with Alpha Preclinical’s expertise and commitment to innovation. Reach out to start your study today.
Technology & Expertise
Alpha Preclinical leverages advanced technologies such as IVIS imaging, alongside expertise in in vivo pharmacology, surgical services, and colony management. Our team, with decades of experience specializes in disease models for gene therapy, oncology, autoimmune diseases, metabolic disorders, inflammation, fibrosis and more. With a robust Quality Management System, we ensure reproducible, high-quality results for preclinical and translational studies, supported by personalized study design and execution.
Core Services
In Vivo Pharmacology: Comprehensive in vivo studies, including efficacy models for oncology, autoimmune, metabolic, and inflammatory diseases. In Vitro Assays: Supportive in vitro services, including cell-based assays and cytotoxicity testing, to complement in vivo research. IVIS Imaging: Advanced imaging for real-time monitoring of disease progression and therapeutic response. Colony Management: Expert management of animal models to ensure study consistency and reliability. Surgical Services: Specialized surgical procedures for complex preclinical models, conducted in a USDA-compliant surgical suite. Custom Study Design: Tailored experimental protocols to address specific research questions and therapeutic areas. Data Analysis & Reporting: Detailed interpretation and reporting of study data to support decision-making and regulatory submissions.
Accreditations & Compliance
Alpha Preclinical adheres to rigorous quality control, sample traceability, and data integrity standards, ensuring compliance with federal, state, and local mandates for preclinical research. Their processes are designed to meet the scientific and regulatory requirements of drug development programs.
