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Zvast Bio
About CRO
Overview
Zvast Biotechnology (ZVAST Bio) is a preclinical contract research organization focused on disease animal model development and early-stage drug evaluation. The team supports biotech and pharma companies with in vivo and in vitro studies designed to generate reliable data for discovery, lead optimization, and IND-enabling programs.
ZVAST Bio emphasizes model accuracy, reproducibility, and customization, working closely with sponsors to align study design with specific scientific and regulatory goals.
Core Services
- Custom disease animal model development
- In vivo pharmacology and efficacy studies
- Mechanism of action and target validation studies
- In vitro ADME services
- In vivo pharmacokinetics (PK)
- Early safety and non-GLP toxicology assessments
Disease Models & Therapeutic Areas
- Oncology (cell-derived xenografts and solid tumor models)
- Dermatology and inflammatory skin diseases
- Immune and autoimmune disorders
- Respiratory diseases
- Metabolic and endocrine disorders
- Cardiovascular diseases
- Neurological and pain models
- Digestive and reproductive system models
The organization maintains a large and growing internal library of validated disease models and regularly develops new models based on client needs.
Facilities & Quality
- Dedicated preclinical research facilities with SPF animal housing
- Integrated in vivo, pathology, and molecular biology laboratories
- Standardized SOPs covering animal welfare, study execution, and data quality
- Quality systems designed to support global drug development and regulatory submissions
Experience & Approach
ZVAST Bio has supported a wide range of biotech and pharmaceutical programs, from exploratory screening studies to more advanced preclinical evaluations. The team is experienced in collaborative project execution, providing study design input, data interpretation support, and clear reporting throughout the engagement.
Best Fit Projects
- Early-stage efficacy screening
- Custom or difficult-to-source animal disease models
- Mechanism-focused in vivo studies
- Pre-IND and IND-supporting pharmacology packages
Technology & Expertise
ZVAST Bio specializes in the development and application of validated disease animal models for preclinical research. The team combines in vivo pharmacology, pathology, and molecular biology expertise to support drug discovery and early development programs. Technical strengths include model customization, study design aligned to biological mechanisms, and data generation focused on reproducibility and decision-making
Core Services
Custom disease animal model development In vivo efficacy and pharmacology studies Mechanism of action and target validation studies In vitro ADME testing In vivo pharmacokinetics (PK) studies Early-stage safety and non-GLP toxicology assessments
Accreditations & Compliance
AAALAC-accredited animal care and use program Standardized SOPs for animal welfare, study execution, and data reporting Quality systems designed to support global preclinical research and regulatory submissions
