Biophysical Assays and Screening

We approach biophysical assays and screening as a decision-focused engagement, not a disconnected list of tasks. Before work begins, we clarify the scientific or operational question, the materials and information already available, the constraints that could affect execution, and the evidence your team needs at the end. That alignment lets us build a practical scope for biophysical assays and screening while keeping the work connected to the broader program.

Our biophysical assays and screening capabilities

This entry-level service offers fast, affordable access to biophysical screening data for up to 2 compounds or protein samples. Ideal for feasibility studies, early discovery, or academic projects needing preliminary binding or stability data. 15-minute consult to discuss results and next steps This work sits within our Assay Development, Laboratory Services capabilities and is coordinated with the wider program context when the scope requires it.

• 1 Assay Type of Your Choice (select from below): Thermal Shift Assay (DSF) – Protein stability and ligand binding
• UV-Vis or Fluorescence Spectroscopy – Quick readouts of sample interaction or conformational changes
• 15-minute consult to discuss results and next steps
• Minimum 100 µL at 1–10 µM concentration
• We will advise on labeling or buffer exchange if needed
• +$250: Include full report with KD estimation (if MST selected)

How we shape the scope

Our planning process connects scientific intent with day-to-day execution. We define the question to be answered, map available inputs to the proposed work, identify review gates, and agree on deliverable formats. We also establish how exceptions, missing information, and unexpected findings will be escalated. This gives your team visibility into the work while allowing our specialists to apply sound judgment as the project develops.

Working with our team

Our team treats communication as part of the technical service. We establish contacts, review points, and escalation paths at the outset, then use them to keep decisions moving. Interim conversations distinguish confirmed findings from working interpretations and unresolved questions. That separation is important: it lets the program team act with appropriate confidence while giving specialists space to investigate observations that require more context.

Deliverables built for the next decision

We build reporting requirements into the project plan instead of treating documentation as an afterthought. The team agrees on what must be captured, who will review it, and how revisions will be resolved. At completion, we organize the outputs around the project objective and provide enough context for qualified stakeholders to understand the work performed and the basis for the conclusions. Any proposed follow-on work is discussed separately, with a clear reason for why it may be useful.

Before execution, we also confirm how the work will connect with adjacent activities and which handoffs could affect quality, timing, or interpretation. That check helps us identify missing inputs early, avoid duplicated effort, and keep the completed package consistent with the program's immediate priorities. We record the decisions made during this alignment so the project team has a stable reference as work progresses.

Planning your biophysical assays and screening project

To plan a biophysical assays and screening project, share the program stage, primary objective, available inputs, known constraints, desired timing, and the decision the work needs to support. We will use that information to frame a focused technical discussion and return a scope that identifies the proposed approach, responsibilities, assumptions, review points, deliverables, and major cost or schedule drivers.