At VitroVivo, our Histopathology Images & Analysis service provides full-spectrum, CRO-quality digital pathology tailored to support preclinical and translational research. Backed by expert scientists and pathologists, we deliver high-fidelity data through advanced imaging, quantitative analysis, and rigorous quality control — enabling confident decision-making across studies.

What We Offer

1. Whole-Slide Scanning & Digital Imaging

• High-resolution whole-slide scanning using state-of-the-art systems (e.g., Olympus VS120)

• Brightfield and fluorescence imaging for a broad range of assays

• Secure, high-capacity storage — digitized slides that are easily shared and archived

2. Molecular & Histology Staining Analysis

• Immunohistochemistry (IHC) — single, dual, or multiplex assays

• Immunofluorescence (IF) for spatial protein expression

• In situ hybridization (FISH / ISH) for DNA/RNA localization

• TUNEL assays for apoptosis and cell death studies

• Special stains (e.g., fibrosis, lipids, extracellular matrix) as needed

3. Quantitative & Visual Scoring

• Expert visual scoring, performed by trained scientists or board-certified pathologists

• Digital quantification: tissue segmentation, cell phenotyping, marker expression levels

• Region-of-interest (ROI) delineation — define and analyze specific tissue compartments (e.g., tumor vs. stroma)

4. Data & Report Delivery

• Final reports with quantitative metrics, statistical summaries, and publication-ready graphics

• Option for raw image data delivery (e.g., whole slide images) for in-depth internal analysis

• Secure data transfer and storage, ensuring data integrity and confidentiality

5. Custom and Advisory Services

• Tailor-made workflows: assay development, optimization, or validation tailored to your project

• Consulting by experienced pathologists to ensure study design and interpretive rigor

• Support for integrating image-based endpoints into biomarker studies or regulatory submissions

Why Choose VitroVivo?

• CRO-Level Reliability: We operate with the consistency, documentation, and reproducibility that pharma and biotech demand.

• Scientific Expertise: Our team includes seasoned histologists, pathologists, and image analysts who understand both biology and technology.

• Scalable Solutions: Whether you need a pilot slide or a large preclinical study, our processes scale seamlessly — from small cohorts to hundreds of slides.

• Transparency & Quality: Through regular updates, quality controls, and open communication, you stay informed every step of the way.

• Secure & Accessible Data: Digitized images and analysis results are managed via secure, compliant systems — ready for review, collaboration, or regulatory use.

Applications & Research Use Cases

• Oncology: tumor microenvironment profiling, biomarker quantitation, therapeutic efficacy

• Immunology: immune cell phenotyping, spatial biology, immune infiltration analysis

• Toxicology: tissue damage assessment, cell death (TUNEL), organ histopathology

• Translational Research: assay validation, biomarker discovery, preclinical-to-clinical bridge